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mouse TTC8 Adenovirus

Name 
Ad-m-TTC8
Cat No 
ADV-275263
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Mouse Ttc8.

ADV-275263
Ad-m-TTC8

Ready-to-use Adenovirus expressing Mouse Ttc8 (tetratricopeptide repeat domain 8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
0610012F22Rik; AV001447; BBS8
Description (Vector)
The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane.
Gene ID
76260
Gene Name (Vector)
tetratricopeptide repeat domain 8
Gene Symbol
Ttc8
ORF Size (aa)
1548
ORF Size (bp)
1548 bp
RefSeq ID
NM_029553
RefSeq Synonyms
NM_198311, NM_029553, BC017523,
Species
mouse
UniGene ID
Mm.282660

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.