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mouse TOP2B Adenovirus

Name 
Ad-m-TOP2B
Cat No 
ADV-274816
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Mouse Top2b.

ADV-274816
Ad-m-TOP2B

Ready-to-use Adenovirus expressing Mouse Top2b (topoisomerase (DNA) II beta). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
D230016L12Rik; Top-2
Description (Vector)
Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Indirectly ivolved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene.
Gene ID
21974
Gene Name (Vector)
topoisomerase (DNA) II beta
Gene Symbol
Top2b
ORF Size (aa)
4839
ORF Size (bp)
4839 bp
RefSeq ID
NM_009409
RefSeq Synonyms
NM_009409, BC054541, BC041106,
Species
mouse
UniGene ID
Mm.130362

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.