mouse TIAM2 Adenovirus

Name 
Ad-m-TIAM2
Cat No 
ADV-274193
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human C8orf46.

ADV-274193
Ad-m-TIAM2

Ready-to-use Adenovirus expressing Mouse Tiam2 (T cell lymphoma invasion and metastasis 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
3000002F19Rik; mKIAA2016; STEF
Description (Vector)
Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Mediates extracellular laminin signals to activate Rac1, contributing to neurite growth. Involved in lamellipodial formation and advancement of the growth cone of embryonic hippocampal neurons. Promotes migration of neurons in the cerebral cortex. When overexpressed, induces membrane ruffling accompanied by the accumulation of actin filaments along the altered plasma membrane (By similarity). Activates specifically RAC1, but not CDC42 and RHOA.
Gene ID
24001
Gene Name (Vector)
T cell lymphoma invasion and metastasis 2
Gene Symbol
Tiam2
ORF Size (aa)
5148
ORF Size (bp)
5148 bp
RefSeq ID
NM_011878
RefSeq Synonyms
NM_011878, NM_001286758, NM_001286757, NM_001122998, BC079600, BC067048,
Species
mouse
UniGene ID
Mm.137134

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.