mouse SUV39H2 Adenovirus
This is an Adenovirus expressing Mouse Suv39h2.
ADV-273486
Ad-m-SUV39H2
Ready-to-use Adenovirus expressing Mouse Suv39h2 (suppressor of variegation 3-9 homolog 2 (Drosophila)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
4930507K23Rik; AA536750; D030054H19Rik; D2Ertd544e; KMT1B
Description (Vector)
Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys-9' as substrate. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric and telomere regions. H3 'Lys-9' trimethylation is also required to direct DNA methylation at pericentric repeats. SUV39H1 is targeted to histone H3 via its interaction with RB1 and is involved in many processes, such as cell cycle regulation, transcriptional repression and regulation of telomere length. May participate in regulation of higher order chromatin organization during spermatogenesis.
Gene ID
64707
Gene Name (Vector)
suppressor of variegation 3-9 homolog 2 (Drosophila)
Gene Symbol
Suv39h2
ORF Size (aa)
774
ORF Size (bp)
774 bp
RefSeq ID
NM_022724
RefSeq Synonyms
NM_022724, BC032960,
Species
mouse
UniGene ID
Mm.441181
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.