mouse RNF2 Adenovirus
This is an Adenovirus expressing Mouse Rnf2.
ADV-270722
Ad-m-RNF2
Ready-to-use Adenovirus expressing Mouse Rnf2 (ring finger protein 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AI326319; AI450156; AU019207; dinG; Ring1B
Description (Vector)
E3 ubiquitin-protein ligase that mediates monoubiquitination of 'Lys-119' of histone H2A, thereby playing a central role in histone code and gene regulation. H2A 'Lys-119' ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals. May be involved in the initiation of both imprinted and random X inactivation. Essential component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, rendering chromatin heritably changed in its expressibility. E3 ubiquitin-protein ligase activity is enhanced by BMI1/PCGF4. Acts as the main E3 ubiquitin ligase on histone H2A of the PRC1 complex, while RING1 may rather act as a modulator of RNF2/RING2 activity.
Gene ID
19821
Gene Name (Vector)
ring finger protein 2
Gene Symbol
Rnf2
ORF Size (aa)
1011
ORF Size (bp)
1011 bp
RefSeq ID
NM_011277
RefSeq Synonyms
NM_011277, BC020122,
Species
mouse
UniGene ID
Mm.441344
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.