mouse RNASEN Adenovirus
This is an Adenovirus expressing Mouse Drosha.
ADV-270656
Ad-m-RNASEN
Ready-to-use Adenovirus expressing Mouse Drosha (drosha, ribonuclease type III). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1110013A17Rik; AI874853; Etohi2; Rn3; Rnasen
Description (Vector)
Ribonuclease III double-stranded (ds) RNA-specific endoribonuclease that is involved in the initial step of microRNA (miRNA) biogenesis. Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus. Within the microprocessor complex, DROSHA cleaves the 3' and 5' strands of a stem-loop in pri-miRNAs (processing center 11 bp from the dsRNA-ssRNA junction) to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs. Involved also in pre-rRNA processing. Cleaves double-strand RNA and does not cleave single-strand RNA. Involved in the formation of GW bodies.
Gene ID
14000
Gene Name (Vector)
drosha, ribonuclease type III
Gene Symbol
Drosha
ORF Size (aa)
4122
ORF Size (bp)
4122 bp
RefSeq ID
NM_026799
RefSeq Synonyms
NM_026799, NM_001130149, BC088999,
Species
mouse
UniGene ID
Mm.293142
Recently Viewed Products
Ad-CMV-iCre
Cat No: 1045
Ad-CMV-Caspase 9 (DN)
Cat No: 1044
Ad-CMV-Rb
Cat No: 1043
Ad-CMV-p27
Cat No: 1042
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.