human CA5A Over-expression AAV

Name
AAV-h-CA5A

Cat No
AAV-203878

Availability
4-5 weeks

This is an AAV expressing Human CA5A.

AAV-203878

AAV-h-CA5A

Ready-to-use AAV expressing Human CA5A (carbonic anhydrase 5A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CA5; CA5AD; CAV; CAVA; GS1-21A4.1

Description (Vector)

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA VA is localized in the mitochondria and expressed primarily in the liver. It may play an important role in ureagenesis and gluconeogenesis. CA5A gene maps to chromosome 16q24.3 and an unprocessed pseudogene has been assigned to 16p12-p11.2.

Gene ID

763

Gene Name (Vector)

carbonic anhydrase 5A

Gene Symbol

CA5A

HGNC ID

HGNC:1377

ORF Size (aa)

918

ORF Size (bp)

918 bp

RefSeq ID

NM_001739

RefSeq Synonyms

NM_001739, BC137411, BC137405,

Species

human

UniGene ID

Hs.177446

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.