mouse PFTK1 Adenovirus

Name
Ad-m-PFTK1

Cat No
ADV-268456

Availability
4-5 weeks

This is an Adenovirus expressing Mouse Cdk14.

ADV-268456

Ad-m-PFTK1

Ready-to-use Adenovirus expressing Mouse Cdk14 (cyclin-dependent kinase 14). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

mKIAA0834; Pftk1

Description (Vector)

Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', leading to the activation of the Wnt signaling pathway. Acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3. Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo. May also play a role in meiosis, neuron differentiation and may indirectly act as a negative regulator of insulin-responsive glucose transport.

Gene ID

18647

Gene Name (Vector)

cyclin-dependent kinase 14

Gene Symbol

Cdk14

ORF Size (aa)

1272

ORF Size (bp)

1272 bp

RefSeq ID

NM_011074

RefSeq Synonyms

NM_011074, NM_001310448, BC068134,

Species

mouse

UniGene ID

Mm.404502

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.