mouse NOTCH4 Adenovirus

Name 
Ad-m-NOTCH4
Cat No 
ADV-265947
Availability
4-5 weeks

This is an Adenovirus expressing Mouse Notch4.

ADV-265947
Ad-m-NOTCH4

Ready-to-use Adenovirus expressing Mouse Notch4 (notch 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
Int-3; Int3; N4
Description (Vector)
Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. May regulate branching morphogenesis in the developing vascular system (By similarity).
Gene ID
18132
Gene Name (Vector)
notch 4
Gene Symbol
Notch4
ORF Size (aa)
5895
ORF Size (bp)
5895 bp
RefSeq ID
NM_010929
RefSeq Synonyms
NM_010929, BC138044,
Species
mouse
UniGene ID
Mm.173813

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.