mouse MDFI Adenovirus

Name
Ad-m-MDFI

Cat No
ADV-264404

Availability
4-5 weeks

This is an Adenovirus expressing Mouse Mdfi.

ADV-264404

Ad-m-MDFI

Ready-to-use Adenovirus expressing Mouse Mdfi (MyoD family inhibitor). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

I-mf; I-mfa

Description (Vector)

Inhibits the transactivation activity of the Myod family of myogenic factors and represses myogenesis. Acts by associating with Myod family members and retaining them in the cytoplasm by masking their nuclear localization signals. Can also interfere with the DNA-binding activity of Myod family members. Plays an important role in trophoblast and chondrogenic differentiation. Regulates the transcriptional activity of TCF7L1/TCF3 by interacting directly with TCF7L1/TCF3 and preventing it from binding DNA. Binds to the axin complex, resulting in an increase in the level of free beta-catenin. Affects axin regulation of the WNT and JNK signaling pathways (By similarity).

Gene ID

17240

Gene Name (Vector)

MyoD family inhibitor

Gene Symbol

Mdfi

ORF Size (aa)

741

ORF Size (bp)

741 bp

RefSeq ID

NM_010783

RefSeq Synonyms

NM_010783, NM_001276391, NM_001276390, NM_001109973, BC085233, BC083058, BC010259, BC006018,

Species

mouse

UniGene ID

Mm.329100

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.