mouse LIMD1 Adenovirus
This is an Adenovirus expressing Human SOCS3.
ADV-263455
Ad-m-LIMD1
Ready-to-use Adenovirus expressing Mouse Limd1 (LIM domains containing 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AW822033; D9Ertd192e
Description (Vector)
Adapter or scaffold protein which participates in the assembly of numerous protein complexes and is involved in several cellular processes such as cell fate determination, cytoskeletal organization, repression of gene transcription, cell-cell adhesion, cell differentiation, proliferation and migration. Positively regulates microRNA (miRNA)-mediated gene silencing and is essential for P-body formation and integrity. Acts as a hypoxic regulator by bridging an association between the prolyl hydroxylases and VHL enabling efficient degradation of HIF1A. Acts as a transcriptional corepressor for SNAI1- and SNAI2/SLUG-dependent repression of E-cadherin transcription. Negatively regulates the Hippo signaling pathway and antagonizes phosphorylation of YAP1. Inhibits E2F-mediated transcription, and suppresses the expression of the majority of genes with E2F1-responsive elements. Regulates osteoblast development, function, differentiation and stress osteoclastogenesis. Enhances the ability of TRAF6 to activate adapter protein complex 1 (AP-1) and negatively regulates the canonical Wnt receptor signaling pathway in osteoblasts. May act as a tumor suppressor by inhibiting cell proliferation.
Gene ID
29806
Gene Name (Vector)
LIM domains containing 1
Gene Symbol
Limd1
ORF Size (aa)
2007
ORF Size (bp)
2007 bp
RefSeq ID
NM_013860
RefSeq Synonyms
NM_013860, BC056449,
Species
mouse
UniGene ID
Mm.10987
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.