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mouse KDM4A Adenovirus

Name 
Ad-m-KDM4A
Cat No 
ADV-262763
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Mouse Kdm4a.

ADV-262763
Ad-m-KDM4A

Ready-to-use Adenovirus expressing Mouse Kdm4a (lysine (K)-specific demethylase 4A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
D4Ertd222e; JHDM3A; Jmjd2; Jmjd2a; mKIAA0677
Description (Vector)
Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. Participates in transcriptional repression of ASCL2 and E2F-responsive promoters via the recruitment of histone deacetylases and NCOR1, respectively.
Gene ID
230674
Gene Name (Vector)
lysine (K)-specific demethylase 4A
Gene Symbol
Kdm4a
ORF Size (aa)
3102
ORF Size (bp)
3102 bp
RefSeq ID
NM_172382
RefSeq Synonyms
NM_172382, NM_001161823, BC028866,
Species
mouse
UniGene ID
Mm.234234

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.