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human C1QC Over-expression AAV

Name 
AAV-h-C1QC
Cat No 
AAV-203136
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human C1QC.

AAV-203136
AAV-h-C1QC

Ready-to-use AAV expressing Human C1QC (complement C1q C chain). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C1Q-C; C1QG
Description (Vector)
C1QC encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. A deficiency in C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N-terminus, and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. C1QC encodes the C-chain polypeptide of human complement subcomponent C1q. Alternatively spliced transcript variants that encode the same protein have been found for this gene.
Gene ID
714
Gene Name (Vector)
complement C1q C chain
Gene Symbol
C1QC
HGNC ID
HGNC:1245
ORF Size (aa)
738
ORF Size (bp)
738 bp
RefSeq ID
NM_172369
RefSeq Synonyms
NM_172369, NM_001347620, NM_001347619, NM_001114101, BC009016,
Species
human
UniGene ID
Hs.467753

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.