mouse FBXO11 Adenovirus

Name 
Ad-m-FBXO11
Cat No 
ADV-259219
Availability
4-5 weeks

This is an Adenovirus expressing Mouse Fbxo11.

ADV-259219
Ad-m-FBXO11

Ready-to-use Adenovirus expressing Mouse Fbxo11 (F-box protein 11). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
C80048; Jf
Description (Vector)
Substrate recognition component of the a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. Binds to and neddylates phosphorylated p53/TP53, inhibiting its transcriptional activity. SCF(FBXO11) does not seem to direct ubiquitination of TP53.
Gene ID
225055
Gene Name (Vector)
F-box protein 11
Gene Symbol
Fbxo11
ORF Size (aa)
2529
ORF Size (bp)
2529 bp
RefSeq ID
NM_001081034
RefSeq Synonyms
NM_001081034, BC128479, BC117885, BC117884,
Species
mouse
UniGene ID
Mm.386857

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.