mouse EYA1 Adenovirus

Name
Ad-m-EYA1

Cat No
ADV-258815

Availability
4-5 weeks

This is an Adenovirus expressing Mouse Eya1.

ADV-258815

Ad-m-EYA1

Ready-to-use Adenovirus expressing Mouse Eya1 (EYA transcriptional coactivator and phosphatase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

bor

Description (Vector)

Tyrosine phosphatase that specifically dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph). 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis. Seems to coactivate SIX2, SIX4 and SIX5. May be required for normal development of branchial arches, ear and kidney.

Gene ID

14048

Gene Name (Vector)

EYA transcriptional coactivator and phosphatase 1

Gene Symbol

Eya1

ORF Size (aa)

1758

ORF Size (bp)

1758 bp

RefSeq ID

NM_010164

RefSeq Synonyms

NM_010164, NM_001310459, NM_001252192, BC066860, BC060260,

Species

mouse

UniGene ID

Mm.250185

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.