mouse EFNB2 Adenovirus

Name
Ad-m-EFNB2

Cat No
ADV-257820

Availability
4-5 weeks

This is an Adenovirus expressing Mouse EFNB2.

ADV-257820

Ad-m-EFNB2

Ready-to-use Adenovirus expressing Mouse Efnb2 (ephrin B2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

ELF-2; Epl5; Eplg5; Htk-L; LERK-5; Lerk5; NLERK-1

Description (Vector)

Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4. Together with EPHB4 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells. May play a role in constraining the orientation of longitudinally projecting axons.

Gene ID

13642

Gene Name (Vector)

ephrin B2

Gene Symbol

Efnb2

ORF Size (aa)

1011

ORF Size (bp)

1011 bp

RefSeq ID

NM_010111

RefSeq Synonyms

NM_010111, BC057009,

Species

mouse

UniGene ID

Mm.209813

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.