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mouse CNGA3 Adenovirus

Name 
Ad-m-CNGA3
Cat No 
ADV-255744
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Mouse Cnga3.

ADV-255744
Ad-m-CNGA3

Ready-to-use Adenovirus expressing Mouse Cnga3 (cyclic nucleotide gated channel alpha 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CNG3
Description (Vector)
Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cyclic GMP which leads to an opening of the cation channel and thereby causing a depolarization of cone photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficacy of the channel when coexpressed with CNGB3 (By similarity). Essential for the generation of light-evoked electrical responses in the red-, green- and blue sensitive cones.
Gene ID
12790
Gene Name (Vector)
cyclic nucleotide gated channel alpha 3
Gene Symbol
Cnga3
ORF Size (aa)
1896
ORF Size (bp)
1896 bp
RefSeq ID
NM_009918
RefSeq Synonyms
NM_009918, NM_001282010, BC049145, BC035272,
Species
mouse
UniGene ID
Mm.214224

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.