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human C10ORF4 Over-expression AAV

Name 
AAV-h-C10ORF4
Cat No 
AAV-202423
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human FRA10AC1.

AAV-202423
AAV-h-C10ORF4

Ready-to-use AAV expressing Human FRA10AC1 (FRA10A associated CGG repeat 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C10orf4; F26C11.1-like; FRA10A; fragile site 10q23.3; fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1; protein FRA10AC1; rare folic acid-type fragile site, FRA(10)(q23.3), candidate gene 1
Description (eCommerce)
FRA10AC1 [fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1] is ubiquitously expressed with higher expression in brain, heart, skeletal muscle, kidney and liver [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q70Z53].
Description (Vector)
FRA10AC1 is a nuclear phosphoprotein of unknown function. The 5' UTR of this gene is part of a CpG island and contains a tandem CGG repeat region that normally consists of 8-14 repeats but can expand to over 200 repeats. The expanded allele becomes hypermethylated and is not transcribed; however, an expanded repeat region has not been associated with any disease phenotype. This gene is found within the rare FRA10A folate-sensitive fragile site.
Gene ID
118924
Gene Name (eCommerce)
FRA10A associated CGG repeat 1
Gene Name (Vector)
FRA10A associated CGG repeat 1
Gene Symbol
FRA10AC1
HGNC ID
HGNC:1162
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
948
ORF Size (bp)
948 bp
Protein Name (eCommerce)
Protein FRA10AC1
RefSeq ID
NM_145246
RefSeq Synonyms
NM_145246, BC018007,
Research Areas
Cell Biology
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
FRA10AC1 [fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1] is ubiquitously expressed with higher expression in brain, heart, skeletal muscle, kidney and liver [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q70Z53].
UniGene ID
Hs.658192
UniProt ID (eCommerce)
Q70Z53

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.