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human BPGM Over-expression AAV

Name 
AAV-h-BPGM
Cat No 
AAV-202237
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human BPGM.

AAV-202237
AAV-h-BPGM

Ready-to-use AAV expressing Human BPGM (bisphosphoglycerate mutase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DPGM
Description (Vector)
2,3-diphosphoglycerate (2,3-DPG) is a small molecule found at high concentrations in red blood cells where it binds to and decreases the oxygen affinity of hemoglobin. This gene encodes a multifunctional enzyme that catalyzes 2,3-DPG synthesis via its synthetase activity, and 2,3-DPG degradation via its phosphatase activity. The enzyme also has phosphoglycerate phosphomutase activity. Deficiency of this enzyme increases the affinity of cells for oxygen. Mutations in this gene result in hemolytic anemia. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Gene ID
669
Gene Name (Vector)
bisphosphoglycerate mutase
Gene Symbol
BPGM
HGNC ID
HGNC:1093
ORF Size (aa)
780
ORF Size (bp)
780 bp
RefSeq ID
NM_001724
RefSeq Synonyms
NM_199186, NM_001724, NM_001293085, BC017050,
Species
human
UniGene ID
Hs.198365

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.