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human BNIP3 Over-expression AAV

Name 
AAV-h-BNIP3
Cat No 
AAV-202214
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human BNIP3.

AAV-202214
AAV-h-BNIP3

Ready-to-use AAV expressing Human BNIP3 (BCL2 interacting protein 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
NIP3
Description (Vector)
BNIP3 is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein, which protects cells from virally-induced cell death. The encoded protein also interacts with E1B 19 kDa-like sequences of BCL2, another apoptotic protector. This protein contains a BH3 domain and a transmembrane domain, which have been associated with pro-apoptotic function. The dimeric mitochondrial protein encoded by this gene is known to induce apoptosis, even in the presence of BCL2.
Gene ID
664
Gene Name (Vector)
BCL2 interacting protein 3
Gene Symbol
BNIP3
HGNC ID
HGNC:1084
ORF Size (aa)
585
ORF Size (bp)
585 bp
RefSeq ID
NM_004052
RefSeq Synonyms
NM_004052, BC021989,
Species
human
UniGene ID
Hs.144873

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.