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human BIRC2 Over-expression AAV

Name 
AAV-h-BIRC2
Cat No 
AAV-202145
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human BIRC2.

AAV-202145
AAV-h-BIRC2

Ready-to-use AAV expressing Human BIRC2 (baculoviral IAP repeat containing 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
API1; c-IAP1; cIAP1; Hiap-2; HIAP2; MIHB; RNF48
Description (Vector)
BIRC2 is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
329
Gene Name (Vector)
baculoviral IAP repeat containing 2
Gene Symbol
BIRC2
HGNC ID
HGNC:590
ORF Size (aa)
1857
ORF Size (bp)
1857 bp
RefSeq ID
NM_001166
RefSeq Synonyms
NM_001256166, NM_001256163, NM_001166, BC028578, BC016174,
Species
human
UniGene ID
Hs.696238

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.