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human BBS2 Over-expression AAV

Name 
AAV-h-BBS2
Cat No 
AAV-201998
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human BBS2.

AAV-201998
AAV-h-BBS2

Ready-to-use AAV expressing Human BBS2 (Bardet-Biedl syndrome 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BBS; RP74
Description (Vector)
BBS2 is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by severe pigmentary retinopathy, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse and the similar phenotypes exhibited by mutations in BBS gene family members is likely due to their shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene forms a multiprotein BBSome complex with six other BBS proteins.
Gene ID
583
Gene Name (Vector)
Bardet-Biedl syndrome 2
Gene Symbol
BBS2
HGNC ID
HGNC:967
ORF Size (aa)
2166
ORF Size (bp)
2166 bp
RefSeq ID
NM_031885
RefSeq Synonyms
NM_031885, BC014140,
Species
human
UniGene ID
Hs.333738

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.