mouse KIDINS220 Adenovirus
This is an Adenovirus expressing Human NOP2.
ADV-250900
Ad-m-KIDINS220
Ready-to-use Adenovirus expressing Mouse Kidins220 (kinase D-interacting substrate 220). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
3110039L19Rik; AI194387; AI316525; C330002I19Rik; mKIAA1250
Description (Vector)
Promotes a prolonged MAP-kinase signaling by neurotrophins through activation of a Rap1-dependent mechanism. Provides a docking site for the CRKL-C3G complex, resulting in Rap1-dependent sustained ERK activation. May play an important role in regulating postsynaptic signal transduction through the syntrophin-mediated localization of receptor tyrosine kinases such as EPHA4. In cooperation with SNTA1 can enhance EPHA4-induced JAK/STAT activation. May play a role in neurotrophin- and ephrin-mediated neuronal outgrowth and in axon guidance during neural development and in neuronal regeneration (By similarity). Modulates stress-induced apoptosis of melanoma cells via regulation of the MEK/ERK signaling pathway.
Gene ID
77480
Gene Name (Vector)
kinase D-interacting substrate 220
Gene Symbol
Kidins220
ORF Size (aa)
5019
ORF Size (bp)
5019 bp
RefSeq ID
NM_001081378
RefSeq Synonyms
NM_001081378, BC157898,
Species
mouse
UniGene ID
Mm.250641
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.