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human BANP Over-expression AAV

Name 
AAV-h-BANP
Cat No 
AAV-201961
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human BANP.

AAV-201961
AAV-h-BANP

Ready-to-use AAV expressing Human BANP (BTG3 associated nuclear protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BEN domain-containing protein 1; BEND1; Btg3-associated nuclear protein; protein BANP; scaffold/matrix-associated region-1-binding protein; SMAR1; SMARBP1
Description (eCommerce)
SMAR1/BANP was identified as a protein that binds the scaffold/matrix associated region of the T-cell receptor beta locus (SMAR1) and as a protein that interacts with BTG3, a member of structurally related proteins that regulate cell proliferation (BANP- BTG-associated nuclear protein). SMAR1/BANP is a DNA binding protein that is reported to be a tumor suppressor and transcriptional repressor. SMAR1/BANP can down-regulate cyclin D1 transcription by binding to the cyclin D1 promoter and through its interaction with HDAC1 (histone deacetylase 1). SMAR1 has also been shown to interact with p53 and modulate its activity.
Description (Vector)
BANP encodes a protein that binds to matrix attachment regions. The protein forms a complex with p53 and negatively regulates p53 transcription, and functions as a tumor suppressor and cell cycle regulator. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
54971
Gene Name (eCommerce)
BTG3 associated nuclear protein
Gene Name (Vector)
BTG3 associated nuclear protein
Gene Symbol
BANP
HGNC ID
HGNC:13450
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1410
ORF Size (bp)
1410 bp
Protein Name (eCommerce)
Protein BANP
RefSeq ID
NM_017869
RefSeq Synonyms
NM_079837, NM_017869, NM_001173543, NM_001173542, NM_001173541, NM_001173540, NM_001173539, BC009424,
Research Areas
Cancer,Cell Cycle,Chromatin Remodeling,Transcription Factor/Regulator,Tumor Suppressors/Oncoproteins
Research Areas (Faceted)
cancer,cell_biology,cell_cycle,genetics,transcription_translation,cancer
Species
human
Target Sentence
SMAR1/BANP was identified as a protein that binds the scaffold/matrix associated region of the T-cell receptor beta locus (SMAR1) and as a protein that interacts with BTG3, a member of structurally related proteins that regulate cell proliferation (BANP- BTG-associated nuclear protein). SMAR1/BANP is a DNA binding protein that is reported to be a tumor suppressor and transcriptional repressor. SMAR1/BANP can down-regulate cyclin D1 transcription by binding to the cyclin D1 promoter and through its interaction with HDAC1 (histone deacetylase 1). SMAR1 has also been shown to interact with p53 and modulate its activity.
UniGene ID
Hs.461705
UniProt ID (eCommerce)
Q8N9N5

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.