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human BAG1 Over-expression AAV

Name 
AAV-h-BAG1
Cat No 
AAV-201934
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human BAG1.

AAV-201934
AAV-h-BAG1

Ready-to-use AAV expressing Human BAG1 (BCL2 associated athanogene 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BAG-1; HAP; RAP46
Description (Vector)
The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X.
Gene ID
573
Gene Name (Vector)
BCL2 associated athanogene 1
Gene Symbol
BAG1
HGNC ID
HGNC:937
ORF Size (aa)
1038
RefSeq ID
NM_004323
RefSeq Synonyms
NM_004323, NM_001172415, BC014774, BC001936,
Species
human
UniGene ID
Hs.377484

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.