human RC3H2 Adenovirus

Name
Ad-h-RC3H2

Cat No
ADV-234397

Availability
4-5 weeks

This is an Adenovirus expressing Human RC3H2.

ADV-234397

Ad-h-RC3H2

Ready-to-use Adenovirus expressing Human RC3H2 (ring finger and CCCH-type domains 2). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

membrane associated DNA binding protein; membrane-associated nucleic acid-binding protein; MNAB; ring finger and CCCH-type zinc finger domain-containing protein 2; ring finger and CCCH-type zinc finger domains 2; RING finger protein 164; RING-type E3 ubiquitin transferase Roquin-2; RNF164; roquin-2

Description (eCommerce)

Roquin-2 is encoded by the gene RC3H2, also known as MNAB. Roquin-2 is a post-transcriptional repressor of mRNAs containing a conserved stem loop motif called the constitutive decay element (CDE). Binding to the CDE promotes mRNA deadenylation and degradation [taken from UniProtKB (Entry: Q9HBD1)].

Gene ID

54542

Gene Name (eCommerce)

ring finger and CCCH-type domains 2

Gene Name (Vector)

ring finger and CCCH-type domains 2

Gene Symbol

RC3H2

HGNC ID

HGNC:21461

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

1521

ORF Size (bp)

1521 bp

Protein Name (eCommerce)

Roquin-2

RefSeq ID

NM_018835

RefSeq Synonyms

NM_018835, NM_001100588, BC044642,

Research Areas

RNA Binding,Zinc-finger

Research Areas (Faceted)

cell_biology

Species

human

Target Sentence

Roquin-2 is encoded by the gene RC3H2, also known as MNAB. Roquin-2 is a post-transcriptional repressor of mRNAs containing a conserved stem loop motif called the constitutive decay element (CDE). Binding to the CDE promotes mRNA deadenylation and degradation [taken from UniProtKB (Entry: Q9HBD1)].

UniProt ID (eCommerce)

Q9HBD1

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.