human TET2 Adenovirus

Name 
Ad-h-TET2
Cat No 
ADV-233047
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human TET2.

ADV-233047
Ad-h-TET2

Ready-to-use Adenovirus expressing Human TET2 (tet methylcytosine dioxygenase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
KIAA1546; MDS; methylcytosine dioxygenase TET2; probable methylcytosine dioxygenase TET2; tet oncogene family member 2
Description (eCommerce)
TET2 (tet methylcytosine dioxygenase 2) catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. TET2 is involved in myelopoiesis, and defects in this gene have been associated with several myeloproliferative disorders [taken from NCBI Entrez Gene (Gene ID: 54790)].
Description (Vector)
TET2 is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defects in this gene have been associated with several myeloproliferative disorders. Two variants encoding different isoforms have been found for this gene.
Gene ID
54790
Gene Name (eCommerce)
tet methylcytosine dioxygenase 2
Gene Name (Vector)
tet methylcytosine dioxygenase 2
Gene Symbol
TET2
HGNC ID
HGNC:25941
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2420
ORF Size (bp)
2420 bp
Protein Name (eCommerce)
Methylcytosine dioxygenase TET2
RefSeq ID
NM_017628
RefSeq Synonyms
NM_017628, NM_001127208, BC110510,
Research Areas
Cancer,Cell Cycle,Epigenetic Regulation of Gene Expression,Metabolism/Metabolic Process,Tumor Suppressors/Oncoproteins
Research Areas (Faceted)
cancer,cell_biology,cell_cycle,genetics,metabolism
Species
human
Target Sentence
TET2 (tet methylcytosine dioxygenase 2) catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. TET2 is involved in myelopoiesis, and defects in this gene have been associated with several myeloproliferative disorders [taken from NCBI Entrez Gene (Gene ID: 54790)].
UniProt ID (eCommerce)
Q6N021

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.