human PLEKHG2 Adenovirus

Name
Ad-h-PLEKHG2

Cat No
ADV-232804

Availability
4-5 weeks

This is an Adenovirus expressing Human PLEKHG2.

ADV-232804

Ad-h-PLEKHG2

Ready-to-use Adenovirus expressing Human PLEKHG2 (pleckstrin homology and RhoGEF domain containing G2). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

ARHGEF42; CLG; common-site lymphoma/leukemia guanine nucleotide exchange factor; CTB-60E11.4; LDAMD; PH domain-containing family G member 2; pleckstrin homology domain containing, family G (with RhoGef domain) member 2; pleckstrin homology domain-containing family G member 2

Description (eCommerce)

PLEKHG2 (pleckstrin homology domain-containing family G member 2) contains a RhoGEF/DH domain and a pleckstrin homology (PH) domain. PH domains are found in proteins involved in cell signaling. PLEKHG2 is proposed to be a guanine-nucleotide exchange factor (GEF) for RAC1/CDC42.

Gene ID

64857

Gene Name (eCommerce)

pleckstrin homology and RhoGEF domain containing G2

Gene Name (Vector)

pleckstrin homology and RhoGEF domain containing G2

Gene Symbol

PLEKHG2

HGNC ID

HGNC:29515

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

2977

ORF Size (bp)

2977 bp

Protein Name (eCommerce)

Pleckstrin homology domain-containing family G member 2

RefSeq ID

NM_022835

RefSeq Synonyms

NM_022835, BC013426,

Research Areas

Apoptosis,Cancer,GPCR Signaling,Neurobiology,NGF Signaling,Rho Signaling,Signal Transduction,Tumor Suppressors/Oncoproteins

Research Areas (Faceted)

cancer,cell_biology,neurobiology,signal_transduction

Species

human

Target Sentence

PLEKHG2 (pleckstrin homology domain-containing family G member 2) contains a RhoGEF/DH domain and a pleckstrin homology (PH) domain. PH domains are found in proteins involved in cell signaling. PLEKHG2 is proposed to be a guanine-nucleotide exchange factor (GEF) for RAC1/CDC42.

UniProt ID (eCommerce)

Q9H7P9

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.