Promotional banner reading 'FALL SAVINGS' with expiry date August 31 on an orange background; features a group of people with orange stacked blocks on the right and discounts for services and catalog products.

human SRGAP1 Adenovirus

Name 
Ad-h-SRGAP1
Cat No 
ADV-229157
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human SRGAP1.

ADV-229157
Ad-h-SRGAP1

Ready-to-use Adenovirus expressing Human SRGAP1 (SLIT-ROBO Rho GTPase activating protein 1). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ARHGAP13; NMTC2; rho GTPase-activating protein 13; SLIT-ROBO Rho GTPase-activating protein 1; srGAP1
Description (eCommerce)
SRGAP1/ARHGAP13 is a member of the srGAP family of proteins that contain a RhoGAP domain, an SH3 domain, and a Fes/CIP4 homology domain and interact with the intracellular domain of roundabout 1 (Robo1). Robo1 is the receptor for Slit signaling and is involved in neuronal cell migration and axon tract positioning. SRGAP1/ARHGAP13 functions to bind and decrease the level of active Cdc42 and RhoA small GTPases during Slit-Robo signaling.
Gene ID
57522
Gene Name (eCommerce)
SLIT-ROBO Rho GTPase activating protein 1
Gene Name (Vector)
SLIT-ROBO Rho GTPase activating protein 1
Gene Symbol
SRGAP1
HGNC ID
HGNC:17382
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3258
ORF Size (bp)
3258 bp
Protein Name (eCommerce)
SLIT-ROBO Rho GTPase-activating protein 1
RefSeq ID
NM_020762
RefSeq Synonyms
NM_020762, NM_001346201, BC053903, BC029919,
Research Areas
Axon Guidance,Neurobiology,Rho Signaling,Signal Transduction
Research Areas (Faceted)
signal_transduction,neurobiology
Species
human
Target Sentence
SRGAP1/ARHGAP13 is a member of the srGAP family of proteins that contain a RhoGAP domain, an SH3 domain, and a Fes/CIP4 homology domain and interact with the intracellular domain of roundabout 1 (Robo1). Robo1 is the receptor for Slit signaling and is involved in neuronal cell migration and axon tract positioning. SRGAP1/ARHGAP13 functions to bind and decrease the level of active Cdc42 and RhoA small GTPases during Slit-Robo signaling.
UniGene ID
Hs.210751
UniProt ID (eCommerce)
Q7Z6B7

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.