human DRAP1 Adenovirus
This is an Adenovirus expressing Human MRC2.
ADV-229148
Ad-h-DRAP1
Ready-to-use Adenovirus expressing Human DRAP1 (DR1 associated protein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
NC2-alpha
Description (Vector)
Transcriptional repression is a general mechanism for regulating transcriptional initiation in organisms ranging from yeast to humans. Accurate initiation of transcription from eukaryotic protein-encoding genes requires the assembly of a large multiprotein complex consisting of RNA polymerase II and general transcription factors such as TFIIA, TFIIB, and TFIID. DR1 is a repressor that interacts with the TATA-binding protein (TBP) of TFIID and prevents the formation of an active transcription complex by precluding the entry of TFIIA and/or TFIIB into the preinitiation complex. The protein encoded by this gene is a corepressor of transcription that interacts with DR1 to enhance DR1-mediated repression. The interaction between this corepressor and DR1 is required for corepressor function and appears to stabilize the TBP-DR1-DNA complex.
Gene ID
10589
Gene Name (Vector)
DR1 associated protein 1
Gene Symbol
DRAP1
HGNC ID
HGNC:3019
ORF Size (aa)
618
RefSeq ID
NM_006442
RefSeq Synonyms
NM_006442, BC010025,
Species
human
UniGene ID
Hs.356742
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.