Promotional banner reading 'FALL SAVINGS' with expiry date August 31 on an orange background; features a group of people with orange stacked blocks on the right and discounts for services and catalog products.

human NPAT Adenovirus

Name 
Ad-h-NPAT
Cat No 
ADV-229030
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human NPAT.

ADV-229030
Ad-h-NPAT

Ready-to-use Adenovirus expressing Human NPAT (nuclear protein, coactivator of histone transcription). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
E14; E14/NPAT; nuclear protein of the ataxia telangiectasia mutated locus; nuclear protein of the ATM locus; nuclear protein, ataxia-telangiectasia locus; nuclear protein, co-activator of histone transcription; p220; protein NPAT
Description (eCommerce)
NPAT (nuclear protein of the ataxia telangiectasia mutated locus) is required for progression through the G1 and S phases of the cell cycle and for S phase entry. It activates transcription of the histone H2A, histone H2B, histone H3 and histone H4 genes in conjunction with MIZF. NPAT also positively regulates the ATM, MIZF and PRKDC promoters. Transcriptional activation may be accomplished at least in part by the recruitment of the NuA4 histone acetyltransferase (HAT) complex to target gene promoters [taken from the Universal Protein Resource (UniProt) ww.uniprot.org/uniprot/Q14207].
Gene ID
4863
Gene Name (eCommerce)
nuclear protein, coactivator of histone transcription
Gene Name (Vector)
nuclear protein, coactivator of histone transcription
Gene Symbol
NPAT
HGNC ID
HGNC:7896
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
4284
ORF Size (bp)
4284 bp
Protein Name (eCommerce)
Protein NPAT
RefSeq ID
NM_002519
RefSeq Synonyms
NM_002519, NM_001321307, BC136270,
Research Areas
Cell Cycle,Gene Expression,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,transcription_translation
Species
human
Target Sentence
NPAT (nuclear protein of the ataxia telangiectasia mutated locus) is required for progression through the G1 and S phases of the cell cycle and for S phase entry. It activates transcription of the histone H2A, histone H2B, histone H3 and histone H4 genes in conjunction with MIZF. NPAT also positively regulates the ATM, MIZF and PRKDC promoters. Transcriptional activation may be accomplished at least in part by the recruitment of the NuA4 histone acetyltransferase (HAT) complex to target gene promoters [taken from the Universal Protein Resource (UniProt) ww.uniprot.org/uniprot/Q14207].
UniGene ID
Hs.171061
UniProt ID (eCommerce)
Q14207

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.