human ZP2 Adenovirus
This is an Adenovirus expressing Human ZP2.
ADV-228971
Ad-h-ZP2
Ready-to-use Adenovirus expressing Human ZP2 (zona pellucida glycoprotein 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Zp-2; ZPA
Description (Vector)
The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The protein encoded by this gene is a structural component of the zona pellucida and functions in secondary binding and penetration of acrosome-reacted spermatozoa. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a consensus furin cleavage site, and a C-terminal transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies.
Gene ID
7783
Gene Name (Vector)
zona pellucida glycoprotein 2
Gene Symbol
ZP2
HGNC ID
HGNC:13188
ORF Size (aa)
2238
ORF Size (bp)
2238 bp
RefSeq ID
NM_003460
RefSeq Synonyms
NM_003460, NM_001290104, BC096307, BC096306, BC096305, BC096304,
Species
human
UniGene ID
Hs.73982
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.