human ASPN Over-expression AAV

Name 
AAV-h-ASPN
Cat No 
AAV-201578
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ASPN.

AAV-201578
AAV-h-ASPN

Ready-to-use AAV expressing Human ASPN (asporin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
OS3; PLAP-1; PLAP1; SLRR1C
Description (Vector)
ASPN encodes a cartilage extracellular protein that is member of the small leucine-rich proteoglycan family. The encoded protein may regulate chondrogenesis by inhibiting transforming growth factor-beta 1-induced gene expression in cartilage. This protein also binds collagen and calcium and may induce collagen mineralization. Polymorphisms in the aspartic acid repeat region of this gene are associated with a susceptibility to osteoarthritis. Alternate splicing results in multiple transcript variants.
Gene ID
54829
Gene Name (Vector)
asporin
Gene Symbol
ASPN
HGNC ID
HGNC:14872
ORF Size (aa)
1155
ORF Size (bp)
1155 bp
RefSeq ID
NM_017680
RefSeq Synonyms
NM_017680, NM_001193335, BC063114,
Species
human
UniGene ID
Hs.435655

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.