human WISP2 Adenovirus
This is an Adenovirus expressing Human WISP2.
ADV-227799
Ad-h-WISP2
Ready-to-use Adenovirus expressing Human WISP2 (WNT1 inducible signaling pathway protein 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CCN5; CT58; CTGF-L
Description (Vector)
WISP2 encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like (CT) domain. The encoded protein lacks the CT domain which is implicated in dimerization and heparin binding. It is 72% identical to the mouse protein at the amino acid level. WISP2 may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Its expression in colon tumors is reduced while the other two WISP members are overexpressed in colon tumors. It is expressed at high levels in bone tissue, and may play an important role in modulating bone turnover.
Gene ID
8839
Gene Name (Vector)
WNT1 inducible signaling pathway protein 2
Gene Symbol
WISP2
HGNC ID
HGNC:12770
ORF Size (aa)
657
RefSeq ID
NM_003881
RefSeq Synonyms
NM_003881, NM_001323370, NM_001323369, BC064379, BC058074, BC017782,
Species
human
UniGene ID
Hs.592145
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.