human ASNA1 Over-expression AAV

Name 
AAV-h-ASNA1
Cat No 
AAV-201566
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ASNA1.

AAV-201566
AAV-h-ASNA1

Ready-to-use AAV expressing Human ASNA1 (arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ARSA1; ARSA-I; Arsenical pump-driving ATPase; Arsenite-stimulated ATPase; ASNA-I; ATPase ASNA1; GET3; golgi to ER traffic 3 homolog; hARSA-I; hASNA-I; transmembrane domain recognition complex 40 kDa ATPase subunit; TRC40
Description (eCommerce)
Arsenical pump-driving ATPase (ASNA1) is the human homolog of the bacterial arsA gene, encoding the arsenite-stimulated ATPase component of the arsenite transporter responsible for resistance to arsenicals. This protein is also a central component of a transmembrane domain (TMD) recognition complex (TRC) that is involved in the post-translational delivery of tail-anchored (TA) proteins from the cytosol to the endoplasmic reticulum (ER). It recognizes and selectively binds the TMD of TA proteins in the cytosol, and delivers them to the ER for insertion [taken from NCBI Entrez Gene (Gene ID: 439)].
Description (Vector)
ASNA1 represents the human homolog of the bacterial arsA gene, encoding the arsenite-stimulated ATPase component of the arsenite transporter responsible for resistance to arsenicals. This protein is also a central component of a transmembrane domain (TMD) recognition complex (TRC) that is involved in the post-translational delivery of tail-anchored (TA) proteins from the cytosol to the endoplasmic reticulum (ER). It recognizes and selectively binds the TMD of TA proteins in the cytosol, and delivers them to the ER for insertion.
Gene ID
439
Gene Name (eCommerce)
arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
Gene Name (Vector)
arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
Gene Symbol
ASNA1
HGNC ID
HGNC:752
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1047
ORF Size (bp)
1047 bp
Protein Name (eCommerce)
ATPase ASNA1
RefSeq ID
NM_004317
RefSeq Synonyms
NM_004317, BC002651,
Research Areas
Cell Biology,Transport
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
Arsenical pump-driving ATPase (ASNA1) is the human homolog of the bacterial arsA gene, encoding the arsenite-stimulated ATPase component of the arsenite transporter responsible for resistance to arsenicals. This protein is also a central component of a transmembrane domain (TMD) recognition complex (TRC) that is involved in the post-translational delivery of tail-anchored (TA) proteins from the cytosol to the endoplasmic reticulum (ER). It recognizes and selectively binds the TMD of TA proteins in the cytosol, and delivers them to the ER for insertion [taken from NCBI Entrez Gene (Gene ID: 439)].
UniGene ID
Hs.465985
UniProt ID (eCommerce)
O43681

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.