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human VNN2 Adenovirus

Name 
Ad-h-VNN2
Cat No 
ADV-227506
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human VNN2.

ADV-227506
Ad-h-VNN2

Ready-to-use Adenovirus expressing Human VNN2 (vanin 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
FOAP-4; GPI-80
Description (Vector)
VNN2 product is a member of the Vanin family of proteins that share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. The encoded protein is a GPI-anchored cell surface molecule that plays a role in transendothelial migration of neutrophils. VNN2 lies in close proximity to, and in same transcriptional orientation as two other vanin genes on chromosome 6q23-q24. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Gene ID
8875
Gene Name (Vector)
vanin 2
Gene Symbol
VNN2
HGNC ID
HGNC:12706
ORF Size (aa)
1563
ORF Size (bp)
1563 bp
RefSeq ID
NM_078488
RefSeq Synonyms
NM_078488, NM_004665, NM_001242350, BC126147, BC126145,
Species
human
UniGene ID
Hs.293130

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.