human VAC14 Adenovirus

Name 
Ad-h-VAC14
Cat No 
ADV-227376
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human VAC14.

ADV-227376
Ad-h-VAC14

Ready-to-use Adenovirus expressing Human VAC14 (Vac14, PIKFYVE complex component). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ArPIKfyve; protein VAC14 homolog; Tax1 (human T-cell leukemia virus type I) binding protein; Tax1-binding protein 2; TAX1BP2; TRX
Description (eCommerce)
The content of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) in endosomal membranes changes dynamically with fission and fusion events that generate or absorb intracellular transport vesicles. VAC14 is a component of a trimolecular complex that tightly regulates the level of PtdIns(3,5)P2. Other components of this complex are the PtdIns(3,5)P2-synthesizing enzyme PIKFYVE (MIM 609414) and the PtdIns(3,5)P2 phosphatase FIG4 (MIM 609390). VAC14 functions as an activator of PIKFYVE (Sbrissa et al., 2007 [PubMed 17556371]) [taken from NCBI Entrez Gene (Gene ID: 55697)].
Description (Vector)
The content of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) in endosomal membranes changes dynamically with fission and fusion events that generate or absorb intracellular transport vesicles. VAC14 is a component of a trimolecular complex that tightly regulates the level of PtdIns(3,5)P2. Other components of this complex are the PtdIns(3,5)P2-synthesizing enzyme PIKFYVE (MIM 609414) and the PtdIns(3,5)P2 phosphatase FIG4 (MIM 609390). VAC14 functions as an activator of PIKFYVE (Sbrissa et al., 2007 (PubMed 17556371)).(supplied by OMIM, Feb 2010)
Gene ID
55697
Gene Name (eCommerce)
Vac14, PIKFYVE complex component
Gene Name (Vector)
Vac14, PIKFYVE complex component
Gene Symbol
VAC14
HGNC ID
HGNC:25507
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2349
ORF Size (bp)
2349 bp
Protein Name (eCommerce)
Protein VAC14 homolog
RefSeq ID
NM_018052
RefSeq Synonyms
NM_018052, BC125109, BC125108, BC007214,
Research Areas
Cancer,Golgi Apparatus,Host-Virus Interactions,Metabolism/Metabolic Process,Signal Transduction,Viral Carcinogenesis
Research Areas (Faceted)
cancer,signal_transduction,cell_biology,infectious_disease,metabolism,cancer,infectious_disease
Species
human
Target Sentence
The content of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) in endosomal membranes changes dynamically with fission and fusion events that generate or absorb intracellular transport vesicles. VAC14 is a component of a trimolecular complex that tightly regulates the level of PtdIns(3,5)P2. Other components of this complex are the PtdIns(3,5)P2-synthesizing enzyme PIKFYVE (MIM 609414) and the PtdIns(3,5)P2 phosphatase FIG4 (MIM 609390). VAC14 functions as an activator of PIKFYVE (Sbrissa et al., 2007 [PubMed 17556371]) [taken from NCBI Entrez Gene (Gene ID: 55697)].
UniGene ID
Hs.445061
UniProt ID (eCommerce)
Q08AM6

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.