human UQCRB Adenovirus

Name
Ad-h-UQCRB

Cat No
ADV-227245

Availability
4-5 weeks

This is an Adenovirus expressing Human UQCRB.

ADV-227245

Ad-h-UQCRB

Ready-to-use Adenovirus expressing Human UQCRB (ubiquinol-cytochrome c reductase binding protein). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

MC3DN3; QCR7; QP-C; QPC; UQBC; UQBP; UQCR6; UQPC

Description (Vector)

UQCRB encodes a subunit of the ubiquinol-cytochrome c oxidoreductase complex, which consists of one mitochondrial-encoded and 10 nuclear-encoded subunits. The protein encoded by this gene binds ubiquinone and participates in the transfer of electrons when ubiquinone is bound. This protein plays an important role in hypoxia-induced angiogenesis through mitochondrial reactive oxygen species-mediated signaling. Mutations in this gene are associated with mitochondrial complex III deficiency. Alternatively spliced transcript variants have been found for this gene. Related pseudogenes have been identified on chromosomes 1, 5 and X.

Gene ID

7381

Gene Name (Vector)

ubiquinol-cytochrome c reductase binding protein

Gene Symbol

UQCRB

HGNC ID

HGNC:12582

ORF Size (aa)

336

RefSeq ID

NM_006294

RefSeq Synonyms

NM_006294, NM_001254752, NM_001199975, BC005230,

Species

human

UniGene ID

Hs.131255

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.