human UPP1 Adenovirus

Name
Ad-h-UPP1

Cat No
ADV-227236

Availability
4-5 weeks

This is an Adenovirus expressing Human UPP1.

ADV-227236

Ad-h-UPP1

Ready-to-use Adenovirus expressing Human UPP1 (uridine phosphorylase 1). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

UDRPASE; UP; UPASE; UPP

Description (Vector)

The 2 known types of pyrimidine nucleoside phosphorylases, uridine phosphorylase (UP; EC 2.4.2.3) and thymidine phosphorylase (TP; EC 2.4.2.4), in the presence of orthophosphate, catalyze the reversible phosphorolysis of uridine and thymidine or deoxyuridine, respectively, to free bases and ribose-1-phosphate or deoxyribose-1-phosphate. Pyrimidine nucleoside phosphorylases can add ribose or deoxyribose to pyrimidine bases to form nucleosides that can be incorporated into RNA or DNA (Watanabe and Uchida, 1995 (PubMed 7488099)).(supplied by OMIM, Aug 2009)

Gene ID

7378

Gene Name (Vector)

uridine phosphorylase 1

Gene Symbol

UPP1

HGNC ID

HGNC:12576

ORF Size (aa)

522

RefSeq ID

NM_003364

RefSeq Synonyms

NM_181597, NM_003364, NM_001287430, NM_001287429, NM_001287428, NM_001287426, BC047030, BC007348, BC001405,

Species

human

UniGene ID

Hs.488240

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.