human ARSA Over-expression AAV

Name
AAV-h-ARSA

Cat No
AAV-201484

Availability
4-5 weeks

This is an AAV expressing Human ARSA.

AAV-201484

AAV-h-ARSA

Ready-to-use AAV expressing Human ARSA (arylsulfatase A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

MLD

Description (Vector)

ARSA hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Alternatively spliced transcript variants have been described for this gene.

Gene ID

410

Gene Name (Vector)

arylsulfatase A

Gene Symbol

ARSA

HGNC ID

HGNC:713

ORF Size (aa)

1524

ORF Size (bp)

1524 bp

RefSeq ID

NM_000487

RefSeq Synonyms

NM_001085428, NM_001085427, NM_001085426, NM_001085425, NM_000487, BC014210,

Species

human

UniGene ID

Hs.88251

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.