human TRPM6 Adenovirus

Name
Ad-h-TRPM6

Cat No
ADV-226557

Availability
4-5 weeks

This is an Adenovirus expressing Human TRPM6.

ADV-226557

Ad-h-TRPM6

Ready-to-use Adenovirus expressing Human TRPM6 (transient receptor potential cation channel subfamily M member 6). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

CHAK2; HMGX; HOMG; HOMG1; HSH

Description (Vector)

TRPM6 is predominantly expressed in the kidney and colon, and encodes a protein containing an ion channel domain and a protein kinase domain. It is crucial for magnesium homeostasis, and plays an essential role in epithelial magnesium transport and in the active magnesium absorption in the gut and kidney. Mutations in this gene are associated with hypomagnesemia with secondary hypocalcemia. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Gene ID

140803

Gene Name (Vector)

transient receptor potential cation channel subfamily M member 6

Gene Symbol

TRPM6

HGNC ID

HGNC:17995

ORF Size (aa)

6066

ORF Size (bp)

6066 bp

RefSeq ID

NM_017662

RefSeq Synonyms

NM_017662, NM_001177311, NM_001177310, BC156137,

Species

human

UniGene ID

Hs.272225

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.