human TRPC3 Adenovirus

Name 
Ad-h-TRPC3
Cat No 
ADV-226538
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human TRPC3.

ADV-226538
Ad-h-TRPC3

Ready-to-use Adenovirus expressing Human TRPC3 (transient receptor potential cation channel subfamily C member 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
hTrp3; hTrp-3; SCA41; short transient receptor potential channel 3; transient receptor potential cation channel subfamily C member 3 variant c; transient receptor protein 3; TRP3; TRP-3; TrpC3
Description (eCommerce)
Transient receptor protein 3 (TRPC3) is thought to form a receptor-activated non-selective calcium permeant cation channel. TRPC3 is probably operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. It is activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C, and by inositol 1,4,5-triphosphate receptors (ITPR) with bound IP3. It may also be activated by internal calcium store depletion [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q13507].
Description (Vector)
TRPC3 is a membrane protein that can form a non-selective channel permeable to calcium and other cations. The encoded protein appears to be induced to form channels by a receptor tyrosine kinase-activated phosphatidylinositol second messenger system and also by depletion of intracellular calcium stores. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
7222
Gene Name (eCommerce)
transient receptor potential cation channel subfamily C member 3
Gene Name (Vector)
transient receptor potential cation channel subfamily C member 3
Gene Symbol
TRPC3
HGNC ID
HGNC:12335
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2547
ORF Size (bp)
2547 bp
Protein Name (eCommerce)
Short transient receptor potential channel 3
RefSeq ID
NM_003305
RefSeq Synonyms
NM_003305, NM_001130698, BC093684, BC093682,
Research Areas
Axon Guidance,Cardiovascular,GPCR Signaling,Neurobiology,Signal Transduction,Transport
Research Areas (Faceted)
cardiovascular,signal_transduction,neurobiology,neurobiology,cell_biology
Species
human
Target Sentence
Transient receptor protein 3 (TRPC3) is thought to form a receptor-activated non-selective calcium permeant cation channel. TRPC3 is probably operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. It is activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C, and by inositol 1,4,5-triphosphate receptors (ITPR) with bound IP3. It may also be activated by internal calcium store depletion [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q13507].
UniGene ID
Hs.150981
UniProt ID (eCommerce)
Q13507

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.