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human TRERF1 Adenovirus

Name 
Ad-h-TRERF1
Cat No 
ADV-226375
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human TRERF1.

ADV-226375
Ad-h-TRERF1

Ready-to-use Adenovirus expressing Human TRERF1 (transcriptional regulating factor 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
BCAR2; breast cancer anti-estrogen resistance 2; dJ139D8.5; HSA277276; RAPA; rapa-1; rapa-2; transcriptional regulating protein 132; transcriptional-regulating factor 1; Transcriptional-regulating protein 132; TREP132; TReP-132; zinc finger protein rapa; zinc finger transcription factor TReP-132
Description (eCommerce)
The transcriptional regulating protein of 132 kDa (TReP-132/TRERF1) was identified as a transcription factor that interacts with and activates the promoter of the CYP11A1 gene, a gene that encodes cytochrome P450 side chain cleavage (P450scc) and catalyzes the first step in steroidgenesis. TRep-132 can function as a nuclear receptor co-activator and has been shown to interact with Sp1 and the progesterone receptor (PR) to suppress growth via activation of the gene promoters of the cyclin-dependent kinase inhibitors, p21 and p27.
Description (Vector)
TRERF1 encodes a zinc-finger transcriptional regulating protein which interacts with CBP/p300 to regulate the human gene CYP11A1.
Gene ID
55809
Gene Name (eCommerce)
transcriptional regulating factor 1
Gene Name (Vector)
transcriptional regulating factor 1
Gene Symbol
TRERF1
HGNC ID
HGNC:18273
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3600
ORF Size (bp)
3600 bp
Protein Name (eCommerce)
Transcriptional-regulating factor 1
RefSeq ID
NM_033502
RefSeq Synonyms
NM_033502, NM_001297573, BC156203,
Research Areas
Metabolism/Metabolic Process,Nuclear Receptor Coactivators,Transcription Factor/Regulator,Zinc-finger
Research Areas (Faceted)
cell_biology,metabolism,transcription_translation
Species
human
Target Sentence
The transcriptional regulating protein of 132 kDa (TReP-132/TRERF1) was identified as a transcription factor that interacts with and activates the promoter of the CYP11A1 gene, a gene that encodes cytochrome P450 side chain cleavage (P450scc) and catalyzes the first step in steroidgenesis. TRep-132 can function as a nuclear receptor co-activator and has been shown to interact with Sp1 and the progesterone receptor (PR) to suppress growth via activation of the gene promoters of the cyclin-dependent kinase inhibitors, p21 and p27.
UniGene ID
Hs.485392
UniProt ID (eCommerce)
Q96PN7

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.