human ARHGEF7 Over-expression AAV

Name 
AAV-h-ARHGEF7
Cat No 
AAV-201375
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ARHGEF7.

AAV-201375
AAV-h-ARHGEF7

Ready-to-use AAV expressing Human ARHGEF7 (Rho guanine nucleotide exchange factor 7). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BETA-PIX; COOL-1; COOL1; Nbla10314; P50; P50BP; P85; P85COOL1; P85SPR; PAK3; PIXB
Description (Vector)
Rho GTPases play a fundamental role in numerous cellular processes triggered by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding protein Rac1 and recruits Rac1 to membrane ruffles and to focal adhesions. This protein can induce membrane ruffling. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Gene ID
8874
Gene Name (Vector)
Rho guanine nucleotide exchange factor 7
Gene Symbol
ARHGEF7
HGNC ID
HGNC:15607
ORF Size (aa)
2262
ORF Size (bp)
2262 bp
RefSeq ID
NM_003899
RefSeq Synonyms
NM_145735, NM_003899, NM_001330598, NM_001330597, NM_001320854, NM_001320853, NM_001320852, NM_001320851, NM_001113513, NM_001113512, NM_001113511, BC060776, BC033905,
Species
human
UniGene ID
Hs.508738

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.