human TICAM1 Adenovirus

Name 
Ad-h-TICAM1
Cat No 
ADV-225491
Availability
4-5 weeks

This is an Adenovirus expressing Human LAYN.

ADV-225491
Ad-h-TICAM1

Ready-to-use Adenovirus expressing Human TICAM1 (toll like receptor adaptor molecule 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
IIAE6; MyD88-3; PRVTIRB; TICAM-1; TRIF
Description (Vector)
TICAM1 encodes an adaptor protein containing a Toll/interleukin-1 receptor (TIR) homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. This protein is involved in native immunity against invading pathogens. It specifically interacts with toll-like receptor 3, but not with other TLRs, and this association mediates dsRNA induction of interferon-beta through activation of nuclear factor kappa-B, during an antiviral immune response.
Gene ID
148022
Gene Name (Vector)
toll like receptor adaptor molecule 1
Gene Symbol
TICAM1
HGNC ID
HGNC:18348
ORF Size (aa)
2139
ORF Size (bp)
2139 bp
RefSeq ID
NM_182919
RefSeq Synonyms
NM_182919, BC136557, BC136556, BC035331,
Species
human
UniGene ID
Hs.29344

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.