human TIAL1 Adenovirus

Name 
Ad-h-TIAL1
Cat No 
ADV-225486
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human LATS2.

ADV-225486
Ad-h-TIAL1

Ready-to-use Adenovirus expressing Human TIAL1 (TIA1 cytotoxic granule associated RNA binding protein like 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
aging-associated gene 7 protein; nucleolysin TIAR; TCBP; T-cluster binding protein; TIA-1-related nucleolysin; TIA-1-related protein; TIAR
Description (eCommerce)
TIA-1 related protein (TIAR) is an RNA-binding protein. TIAR is also called nucleolysin and possesses nucleolytic activity against cytotoxic lymphocyte target cells. TIAR may be involved in apoptosis [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q01085].
Description (Vector)
TIAL1 is a member of a family of RNA-binding proteins, has three RNA recognition motifs (RRMs), and binds adenine and uridine-rich elements in mRNA and pre-mRNAs of a wide range of genes. It regulates various activities including translational control, splicing and apoptosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The different isoforms have been show to function differently with respect to post-transcriptional silencing.
Gene ID
7073
Gene Name (eCommerce)
TIA1 cytotoxic granule associated RNA binding protein like 1
Gene Name (Vector)
TIA1 cytotoxic granule associated RNA binding protein like 1
Gene Symbol
TIAL1
HGNC ID
HGNC:11804
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
759
Protein Name (eCommerce)
Nucleolysin TIAR
RefSeq ID
NM_003252
RefSeq Synonyms
NM_003252, NM_001323970, NM_001323969, NM_001323968, NM_001323967, NM_001323965, NM_001323964, NM_001033925, BC030025,
Research Areas
Apoptosis,Lysosome,RNA Binding,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
TIA-1 related protein (TIAR) is an RNA-binding protein. TIAR is also called nucleolysin and possesses nucleolytic activity against cytotoxic lymphocyte target cells. TIAR may be involved in apoptosis [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q01085].
UniGene ID
Hs.501203
UniProt ID (eCommerce)
Q01085

Related Citations

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.