human ARHGAP12 Over-expression AAV

Name 
AAV-h-ARHGAP12
Cat No 
AAV-201307
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ARHGAP12.

AAV-201307
AAV-h-ARHGAP12

Ready-to-use AAV expressing Human ARHGAP12 (Rho GTPase activating protein 12). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
rho GTPase-activating protein 12; rho-type GTPase-activating protein 12
Description (eCommerce)
ARHGAP12 is a member of a large family of proteins that activate Rho-type guanosine triphosphate (GTP) metabolizing enzymes. ARHGAP12 may be involved in suppressing tumor formation by regulating cell invasion and adhesion [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8IWW6].
Description (Vector)
ARHGAP12 encodes a member of a large family of proteins that activate Rho-type guanosine triphosphate (GTP) metabolizing enzymes. The encoded protein may be involved in suppressing tumor formation by regulating cell invasion and adhesion. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene ID
94134
Gene Name (eCommerce)
Rho GTPase activating protein 12
Gene Name (Vector)
Rho GTPase activating protein 12
Gene Symbol
ARHGAP12
HGNC ID
HGNC:16348
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2400
ORF Size (bp)
2400 bp
Protein Name (eCommerce)
Rho GTPase-activating protein 12
RefSeq ID
NM_018287
RefSeq Synonyms
NM_018287, NM_001270699, NM_001270698, NM_001270697, NM_001270696, NM_001270695, BC115363, BC115362, BC094719,
Research Areas
Signal Transduction
Research Areas (Faceted)
signal_transduction
Species
human
Target Sentence
ARHGAP12 is a member of a large family of proteins that activate Rho-type guanosine triphosphate (GTP) metabolizing enzymes. ARHGAP12 may be involved in suppressing tumor formation by regulating cell invasion and adhesion [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8IWW6].
UniGene ID
Hs.499264
UniProt ID (eCommerce)
Q8IWW6

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.