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human TBCC Adenovirus

Name 
Ad-h-TBCC
Cat No 
ADV-225116
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human TBCC.

ADV-225116
Ad-h-TBCC

Ready-to-use Adenovirus expressing Human TBCC (tubulin folding cofactor C). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CFC; Tubulin-folding cofactor C; tubulin-specific chaperone C
Description (eCommerce)
Tubulin-folding cofactor C is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state [taken from NCBI Entrez Gene (Gene ID: 6903)].
Description (Vector)
Cofactor C is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state.
Gene ID
6903
Gene Name (eCommerce)
tubulin folding cofactor C
Gene Name (Vector)
tubulin folding cofactor C
Gene Symbol
TBCC
HGNC ID
HGNC:11580
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1041
ORF Size (bp)
1041 bp
Protein Name (eCommerce)
Tubulin-specific chaperone C
RefSeq ID
NM_003192
RefSeq Synonyms
NM_003192, BC020170, BC017479,
Research Areas
Cytoskeleton,Metabolism/Metabolic Process,Protein Folding,Translational Control
Research Areas (Faceted)
cell_biology,metabolism,transcription_translation
Species
human
Target Sentence
Tubulin-folding cofactor C is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state [taken from NCBI Entrez Gene (Gene ID: 6903)].
UniGene ID
Hs.75064
UniProt ID (eCommerce)
Q15814

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.