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human SUPT5H Adenovirus

Name 
Ad-h-SUPT5H
Cat No 
ADV-224751
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human SUPT5H.

ADV-224751
Ad-h-SUPT5H

Ready-to-use Adenovirus expressing Human SUPT5H (SPT5 homolog, DSIF elongation factor subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
DRB sensitivity-inducing factor 160 kDa subunit; DRB sensitivity-inducing factor large subunit; DSIF large subunit; DSIF p160; hSPT5; SPT5; SPT5H; suppressor of Ty 5 homolog; Tat-cotransactivator 1 protein; Tat-CT1; Tat-CT1 protein; transcription elongation factor SPT5
Description (eCommerce)
Transcription elongation is one step in the multistage process of transcription that involves the polymerization of nucleoside monophosphates into a ribonucleotide transcript catalyzed by the multisubunit complex RNA Pol II. Transcriptional regulation involves positive factors that promote sufficient elongation rates and processivity as well as negative elongation factors that repress transcription elongation. SUPT5H is a subunit of the DRB sensitivity inducing factor (DSIF) along with SUPT4H that functions as a negative elongation factor. DSIF associates with RNA Pol II and may inhibit elongation by pausing and terminating RNA Pol II activity.
Gene ID
6829
Gene Name (eCommerce)
SPT5 homolog, DSIF elongation factor subunit
Gene Name (Vector)
SPT5 homolog, DSIF elongation factor subunit
Gene Symbol
SUPT5H
HGNC ID
HGNC:11469
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3264
ORF Size (bp)
3264 bp
Protein Name (eCommerce)
Transcription elongation factor SPT5
RefSeq ID
NM_003169
RefSeq Synonyms
NM_003169, NM_001319991, NM_001319990, NM_001130825, NM_001130824, NM_001111020, BC024203,
Research Areas
Autophagy,Cell Cycle,Chromatin Remodeling,Gene Expression,Host-Virus Interactions,mRNA Processing,RNA Processing,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,infectious_disease,transcription_translation
Species
human
Target Sentence
Transcription elongation is one step in the multistage process of transcription that involves the polymerization of nucleoside monophosphates into a ribonucleotide transcript catalyzed by the multisubunit complex RNA Pol II. Transcriptional regulation involves positive factors that promote sufficient elongation rates and processivity as well as negative elongation factors that repress transcription elongation. SUPT5H is a subunit of the DRB sensitivity inducing factor (DSIF) along with SUPT4H that functions as a negative elongation factor. DSIF associates with RNA Pol II and may inhibit elongation by pausing and terminating RNA Pol II activity.
UniGene ID
Hs.631604
UniProt ID (eCommerce)
O00267

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.