human APRT Over-expression AAV

Name 
AAV-h-APRT
Cat No 
AAV-201225
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human APRT.

AAV-201225
AAV-h-APRT

Ready-to-use AAV expressing Human APRT (adenine phosphoribosyltransferase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AMP; APRTD
Description (Vector)
Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
353
Gene Name (Vector)
adenine phosphoribosyltransferase
Gene Symbol
APRT
HGNC ID
HGNC:626
ORF Size (aa)
543
ORF Size (bp)
543 bp
RefSeq ID
NM_000485
RefSeq Synonyms
NM_001030018, NM_000485, BC107151, BC106894,
Species
human
UniGene ID
Hs.28914

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.